A team of renowned scientific experts has joined forces from across the world to help fight the spread of misinformation about the COVID-19 vaccines, which hold the key to beating the deadly pandemic and releasing countries from debilitating lockdown restrictions. Together they have created a unique online guide, The COVID-19 Vaccine Communication Handbook, to arm people with practical tips combined with the latest information and evidence to talk reliably about the vaccines, constructively challenge myths, and allay related fears.